A mphibians—frogs, toads, and salamanders—have been around for a long time. They watched the dinosaurs come and go. But today amphibian populations around the world are in dramatic decline, with more than a third of the world’s amphibian species threatened with extinction. Why? Biologists work to answer this question by making observations and doing experiments. A number of factors may be involved, and one possible cause may be the effects of agricultural pesticides and herbicides. Several studies have shown that many of these chemicals tested at realistic concentrations do not kill amphibians. But Tyrone Hayes, a biologist at the University of California at Berkeley, probed deeper. Hayes fo cused on atrazine, the most widely used herbicide in the world and a common contaminant in fresh water. More than 70 million pounds of atrazine are applied to farmland in the United States every year, and it is used in at least 20 countries. Atrazine is usually applied in the spring, w...